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Case report

Treatment of hepatitis C in two paediatric patients using sofosbuvir during haematopoietic stem cell transplantation

Antonio G Grasso, Aurelio Sonzogni, Davide Zanon, Alessandra Maestro, Stefano Loiacono, Natalia Maximova

Corresponding author name: Natalia Maximova
Corresponding author e-mail: natalia.maximova@burlo.trieste.it

Citation: Antiviral Therapy 2019; 24:603-607
doi: 10.3851/IMP3332

Date accepted: 17 June 2019
Date published online: 11 September 2019

Abstract

We report the first two paediatric cases of sofosbuvir treatment during high-intensity myeloablative conditioning and engraftment phases of haematopoietic stem cell transplantation. These reports highlight the safety of sofosbuvir during all phases of transplantation and the lack of interaction between sofosbuvir and alkylating or immunosuppressive agents.

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