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Antiviral effect of maraviroc in semen: a case report

Christophe Pasquier, Nathalie Moinard, Karine Sauné, Myriam Daudin, Stéphanie Trancart, Patrice Massip, Jacques Izopet, Louis Bujan

Corresponding author name: Christophe Pasquier
Corresponding author e-mail: pasquier.c@chu-toulouse.fr

Citation: Antiviral Therapy 2012; 17:933-936
doi: 10.3851/IMP2038

Date accepted: 10 October 2011
Date published online: 01 February 2012


We describe the antiviral effect of maraviroc in a patient who had been shedding high levels of HIV-1 in seminal fluid for three years despite an undetectable blood plasma viral load. Adding maraviroc to HAART stopped the seminal shedding. We discuss the mechanisms involved and the effect on sexual transmission.


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