|2020 Plenary speakers|
COVID-19: Public Health and Scientific Challenges
Probing the impact of HIV infection on adipose tissue function in the era of precision metabolic health
Molecular physiology of body weight homeostasis in humans
Population Differences in Sleep Health and Implications for Well-being and Health Status
In vivo measurement of energy metabolism in heart and skeletal muscle
Children and Adolescents: Focus on HIV-associated co-morbidities: What will the future hold?
Anthony S. Fauci, M.D. is director of the National Institute of Allergy and Infectious Diseases (NIAID) at the U.S. National Institutes of Health, where he oversees an extensive research portfolio focused on infectious and immune-mediated diseases. As the long-time chief of the NIAID Laboratory of Immunoregulation, Dr. Fauci has made many seminal contributions in basic and clinical research and is one of the world’s most-cited biomedical scientists. He was one of the principal architects of the President’s Emergency Plan for AIDS Relief (PEPFAR), a program that has saved millions of lives throughout the developing world.
Suneil Koliwad, MD, PhD is an Associate Professor of Medicine at the University of California San Francisco and an investigator in the UCSF Diabetes Center. He holds the Gerold Grodsky, PhD/JAB Chair in Diabetes Research, and is a board certified endocrinologist attending on the Diabetes and Endocrinology Services at The Zuckerberg San Francisco General Hospital. Dr. Koliwad’s lab focuses on the how nutrients, inflammation, and metabolism intersect to produce serious diseases, such as diabetes, that are linked to obesity. His group aims to find innovative ways to manipulate such metabolic inflammation to mitigate obesity, diabetes, heart disease, and fatty liver. His group is also focused on how to tailor preventative approaches to specific populations that bear a disproportionately high risk for diabetes. This “precision medicine” research program includes probing the specific impact of HIV infection on human adiposity, adipose tissue metabolic function, and diabetes risk.
Dr. Leibel is Christopher J. Murphy Memorial Professor of Diabetes Research, Professor of Pediatrics and Medicine at Columbia University Medical Center, and Head of the Division of Molecular Genetics in the Department of Pediatrics. He is also Co-Director of the Naomi Berrie Diabetes Center and, PI of the NIH New York Nutrition Obesity Research Center.
Dr. Leibel’s research has related to adipose tissue biochemistry and cellular physiology, the molecular genetics of control of body weight in rodents and humans, the bioenergetics of body weight regulation in humans and the role of leptin in these processes, including the metabolic and behavioral responses to maintenance of a reduced body weight.
He and his associates have:
- Cloned and characterized a number of genes in the pathways regulating body weight and modifying diabetes susceptibility, contributing in particular to the molecular cloning and characterization of the leptin and leptin receptor genes. He has continued to pursue the molecular physiology of the “leptin axis” in body weight regulation. In animals and humans.
- Identified the macrophage as the major cellular source of cytokines in adipose tissue.
- Generated islets and neurons from iPSCs derived from patients with monogenic mutations causing diabetes or obesity. These cells have been shown to recapitulate the anticipated seminal phenotypes of the patients from whom they were derived
- Used mouse and cell-based systems to examine the mechanism(s) by which intronic variation in FTO contributes to obesity.
He is a member of the National Academy of Medicine, and has served as a member of the Federal Advisory Council for NIDDK and as an Associate Editor of the Journal of Clinical Investigation. He is a member of the NY Governor’s Life Science Advisory Board. His research is supported by the NIH, the Russell Berrie Foundation, the Weezie Foundation, the NY Community Trust, Regeneron Inc and Levo Therapeutics.
Susan Redline, MD, MPH, is the Peter C. Farrell Professor of Sleep Medicine at Harvard Medical School. She directs Programs in Sleep and Cardiovascular Medicine and Sleep Medicine Epidemiology at Brigham and Women's Hospital and Beth Israel Deaconess Medical Center. Dr. Redline’s research includes epidemiological studies and clinical trials designed to 1) elucidate the etiologies of sleep disorders, including the role of genetic and early life developmental factors; and 2) understand the cardiovascular and other health outcomes of sleep disorders and the role of sleep interventions in improving health. She leads the Sleep Reading Center for a number of major NIH multicenter studies, including the Sleep Heart Health Study, and has led several large cohort studies, including the Cleveland Children’s Sleep and Health Study. She has published over 500 peer-reviewed articles and has served the sleep research community in a number of capacities, including as a member of the Boards of Directors for the American Academy of Sleep Medicine and the Sleep Research Society, the NIH's Sleep Disorders Research Advisory Board, the Institute of Medicine's Committee on Sleep Medicine and Research, and Deputy Editor for the journal Sleep. She received BS and M.D. degrees from Boston University, an MPH degree from Harvard School of Public Health, completed internal medicine and pulmonary and critical care medicine training at Case Western Reserve University, and a research fellowship in Respiratory Epidemiology at Harvard Medical School.
Professor Zühlke is a paediatric cardiologist in the Dept. of Paediatric Cardiology at Red Cross Children’s Hospital and directs the Children’s Heart Disease Research Unit focused on family-centred research into Children’s Heart Diseases of relevance in Africa. Her research projects span congenital and Rheumatic Heart disease, HIV in adolescents, Grown-up Congenital heart disease and cardiac disease in women of childbearing age. She was the recipient of the 2018 MRC/Dfid African research leader Award. She is the only female full Professor of Paediatric Cardiology in her country and is passionate about mentoring women and minority groups in Cardiology practice and leadership. She has delivered several talks in this regard and is part of the Lancet commission for Cardiovascular disease in Women. A speaker at all the premier international cardiology congresses, she recently delivered a lecture to the Academy of Medical Sciences in London on “Developing capacity for clinical research in low and middle-income countries”, another personal passion and was a designated rising star at the Gates Grand Challenges meeting held in Ethiopia in October 2019. She leads the PROTEA study” Partnerships for Congenital Heart Disease in Africa” focusing on describing the epidemiology and genetic origins of Congenital Heart Disease in several countries in Africa.