4th International Congress on Abdominal Obesity

TARGETING GUT HORMONES

Effects on appetite, weight and cardiometabolic outcomes

15:00–17:00, 12 September 2013, Convention Hall C (4F), Grand Hilton Seoul, South Korea

Chair: Luc Van Gaal, Antwerp, Belgium

In this symposium, Professors Van Gaal, Carpentier and Chan will review the interaction of gut hormones with appetite control centers in the brain in the regulation of appetite, feeding behaviours and energy metabolism. By improving our understanding of the complex hormonal and neuronal responses within the gut-brain axis, it may be possible to optimize established weight management interventions, including lifestyle measures and bariatric surgery, as well as develop treatments that complement the options currently available for obese or overweight people.

The development of pharmacological approaches to weight loss has been challenging. A number of new agents targeting different points in the gut-brain axis have recently been launched or are at an advanced stage of development. The therapeutic utility of targeting the gut-brain axis is also well established in the treatment of type 2 diabetes. We will review the evidence from clinical studies in obesity and in diabetes to consider the potential role of pharmacotherapy in tailored weight management strategies.

Learning objectives

  • Raise awareness of the clinical effects of treatments targeting gut hormone signaling
  • Assist physicians in implementing tailored treatment strategies for improved outcomes
15:00–15:05 Introduction and welcome Luc Van Gaal
Antwerp, Belgium
15:05–15:30 Addressing multifactorial risks in obesity/
cardiometabolic disease
Juliana Chan
Hong Kong, SAR China
15:30–15:55 Pharmacotherapy for weight management:
past, present and future
Luc Van Gaal
Antwerp, Belgium
15:55–16:20 Gut hormones in the anti-diabetic effects
of bariatric surgery
André Carpentier
Sherbrooke, Canada
16:20–16:50 Interactive case study: presentation highlighting
challenges of obesity management
All
16:50–17:00 Group discussion All